Detox & Cleanse IV Therapy in Sioux FallsSouth Dakota
2 providers offering detox & cleanse in Sioux Falls. Typical pricing: $199 - $399.
2
Detox & Cleanse Providers
2
Clinics
$160+
Starting From
Detox & Cleanse Providers in Sioux Falls
ivclub - iv&co.
Premier elective IV therapy provider specializing in customized nutrient infusions delivered by registered RNs using only the highest quality medical supplies. Known for their 'Let's Experiment' personalized cocktail approach where clients can build their own IV blend from 20+ ingredients.

Ozone Therapy | Boost Wellness and Detox at iv&co - ivclub
Other IV Therapy Providers in Sioux Falls
These providers offer IV therapy in Sioux Falls and may also provide detox & cleanse.
Nurse Nicole& The L.A.B.
Prime IV Hydration & Wellness - Sioux Falls
Premium IV therapy provider offering personalized wellness treatments in a spa-like environment with zero-gravity massage chairs. They specialize in high-quality IV infusions, NAD+ therapies, and customized wellness plans delivered by professional infusion specialists.

Contact – ivclub - DBA iv&co.

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Accelerate Wellness - Longevity Medicine Clinic
Combines traditional, functional, and evidence-based longevity medicine to deliver personalized whole-body care designed to support hormone balance, metabolism, and long-term vitality. Services are delivered by certified providers accessible both in-person and via telehealth.

New downtown IV clinic specializes in mobile service
A new downtown IV clinic is finding a niche bringing IV hydration therapy and vitamin injections directly to customers.
The Wellness Collective
The Wellness Collective integrates counseling, psychiatry, functional medicine, massage, nutrition, IV therapy, and yoga to improve physical, emotional, and mental well-being. We're your local best in Sioux Falls!

iv&co.
Infinity Medical Aesthetics
Luxury medical spa offering the widest variety of advanced Sciton lasers, Coolsculpting Elite, dermal fillers, and neuromodulator treatments in the area, with an educated and welcoming team led by Dr. Brittany Wangsness, who has access to Allergan Medical Institute's only trainer in South Dakota.

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Vital Flow Infusions
Physician-owned and medically supervised IV hydration therapy provider offering custom IV drips, vitamin injections, weight loss medications, and NAD+ therapy in a comfortable lounge environment with registered nurses on-site.
LIVE Hydration Spa Sioux Falls
A premier IV hydration spa offering expert-guided IV therapy packages and specialized treatments. LIVE Hydration Spa sets the gold standard for IV therapy experiences by combining professional medical care with customer-centric wellness choices across cosmetic, wellness, acute, and athletic categories.
Divinity Wellness Center
A holistic wellness center that treats the whole person using five core principles: Movement, Nutrition, Neural Function, Decreasing Stress, and Decreasing Toxicity. They use entirely natural, God-centered healing methods that amplify the body's innate ability to heal itself.
The Confidence Collective
A medical aesthetics practice specializing in strategic, precision-based injectables and aesthetic treatments led by board-certified Women's Health Nurse Practitioner Stacy Bissoon. They focus on subtle, natural-looking enhancements that emphasize facial harmony and confidence over perfection.

Storm Clinic
Dear Storm Clinic / Allure Health patients and/or representatives,

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Revive Functional Medicine
Certified Functional Medicine experts specializing in root cause analysis for women with gut and hormonal imbalances. All services are virtual, using advanced lab testing and personalized coaching to help clients understand and resolve health issues traditional doctors may have missed.
Encompass Wellness & Aesthetics
A wellness clinic blending modern medicine, advanced aesthetics, and personalized care with a focus on root causes and whole-body health. Known for expert, tailored treatments delivered by experienced practitioners like Mary J. Jordan, ARNP.
Liv Med Spa | Sioux Falls, SD
Liv Med Spa specializes in expertly crafted injectable treatments and aesthetic procedures designed to help clients feel confident in their skin. They emphasize personalized treatment plans and a welcoming, comfortable experience for every client.

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IV Therapy Services | Hydration, Wellness, & Recovery iv&co

IV Therapy / Vitamin Shots in Sioux Falls — SOZO wellness
Book an IV therapy or vitamin shot session in Sioux Falls at SOZO wellness to boost your health and hydration.
Avera Infusion Center — Plaza 1
What is Detox & Cleanse IV Therapy?
Detox IV therapy delivers glutathione, vitamin C, and other antioxidants to support the body's natural detoxification pathways. Glutathione, often called the 'master antioxidant,' plays a central role in liver detoxification, free radical neutralization, and cellular repair.
Benefits
- Glutathione is the body's most powerful natural antioxidant
- Supports liver function and detoxification pathways
- Neutralizes free radicals and reduces oxidative stress
- May improve skin brightness as a secondary benefit
- Helps recovery from environmental toxin exposure
$199 - $399
30 - 60 minutes
What to Expect
The detox drip typically includes glutathione (often given as a separate push at the end of the IV) along with vitamin C, B-vitamins, and hydrating fluids. Sessions run 30-60 minutes. Some patients notice improved energy and mental clarity within 24 hours. Skin brightening effects from glutathione become more apparent with repeated sessions.
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Claim Free ListingFrequently Asked Questions
What does glutathione do?
Glutathione is a tripeptide antioxidant produced naturally in the liver. It neutralizes free radicals, supports Phase II liver detoxification, recycles other antioxidants (like vitamins C and E), and plays a role in immune cell function. IV delivery bypasses poor oral absorption of supplemental glutathione.
How often should I get detox IVs?
For general wellness, monthly sessions are common. For specific detox goals or skin brightening, weekly sessions for 4-6 weeks followed by monthly maintenance is a typical protocol. Your provider can recommend a schedule based on your health goals.
How many detox & cleanse providers are in Sioux Falls?
There are 2 detox & cleanse providers in Sioux Falls, South Dakota, plus 24 other IV therapy providers in the area.
How much does detox & cleanse cost in Sioux Falls?
Detox & Cleanse in Sioux Falls starts at $160. The typical national price range is $199 - $399. Prices vary by provider, add-ons, and whether you choose mobile or in-clinic service.